Composition
Each tablet contains-
- Dried Aluminium Hydroxide Gel BP (Al2O3, 47% minimum): 425.53 mg
- Magnesium Hydroxide BP: 400 mg
- Simethicone USP: 30 mg
Each 5 ml contains-
- Aluminium Oxide (Equivalent amount of Aluminium Hydroxide Gel USP): 200 mg
- Magnesium Hydroxide (Equivalent amount of Magnesium Hydroxide Paste USP): 400 mg
- Simethicone USP: 30 mg
Indications
Therapeutic Class
Pharmacology
This is the mixture of non-systemic acid neutralizing substances and antiflatulent. This preparation offers reliability as well as long action. Aluminium Hydroxide and Magnesium Hydroxide induce the relief of ulcer by neutralizing gastric acid secreted from parietal cells of the stomach. The clinical use of simethicone is based on its antifoam properties. Simethicone spreads on the surface of aqueous liquids, forming a film of low surface tension and causing collapse of foam bubbles. Simethicone repeatedly allows mucous surrounded gas bubbles in the GI tract to coalesce and be expelled.
This is used in the treatment of flatulence and meteorism for the elimination of gas, air or foam from the gastro-intestinal tract prior to radiography and for the relief of abdominal distension and dyspepsia.
Simethicone is physiologically inert; it does not appeared to be absorbed from the GI tract to interfere with gastric secretion or absorption of nutrients. Following oral administration, the drug is excreted unchanged in the feces.
Dosage & Administration
Tablet: 1-2 tablets 1-3 hours after meal and at bed time or as directed by the physician.
Suspension: 1-2 teaspoonful 1-3 hours after meal and at bedtime or as directed by the physician.
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