Indications
Therapeutic Class
Pharmacology
Sodium Alginate is a naturally occurring substance. It reacts with the acid in the stomach to form a gel. Potassium Bicarbonate also reacts with the acid in the stomach to form bubbles of carbon dioxide. These bubbles are trapped by the gel formed by Soodium Alginate and they allow the gel to float like a raft on top of the stomach contents. The raft prevents acid in the stomach from flowing back into the food pipe. This relieves the symptoms of reflux such as heartburn.
The mode of action of this preparation is physical and does not depend on absorption into the systemic circulation.The raft lasts for up to 4 hours on top of the stomach contents and is then broken down in the digestive system and excreted in the feces.
Dosage & Administration
Tablet:
- Adult and child over 12 years: 1-2 tablets daily 4 times, after meals and at bed time.
- Child 6-12 years: 1 tablet daily 4 times, after meals and at bed time.
Suspension:
- Adult and child over 12 years: 5-10 ml daily 4 times, after meals and at bedtime.
- Child 2-12 years: 2.5-5 ml daily 4 times, after meals and at bedtime. This is not recommended for children under 2 years of age.
Interaction
Contraindications
Side Effects
Pregnancy & Lactation
- Pregnancy: This combination may be used during pregnancy.
- Breast feeding: No known effect on breast fed infants. Can be used during breast feeding.
- Fertility: No known effect on human fertility.
Precautions & Warnings
Each 10 ml (two teaspoonfuls) or two-tablet dose has a sodium content of 106 mg and a potassium content of 78 mg. This should be taken into account when a highly restricted salt diet is recommended, e.g. in some cases of congestive cardiac failure and renal impairment or when taking drugs which can increase plasma potassium levels.
Each 10 ml or two-tablet dose contains 200 mg of calcium carbonate. Care needs to be taken in treating patients with hypercalcemia, nephrocalcinosis and recurrent calcium containing renal calculi.
There is a possibility of reduced efficacy in patients with very low levels of gastric acid. If symptoms do not improve after seven days, the clinical situation should be reviewed.
Use in Special Populations
Elderly: No dose modifications necessary for this age group.
Hepatic Impairment: No dose modifications necessary.
Renal Insufficiency: Caution if highly restricted salt diet is necessary.
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